AB1606 SYMPTOMS OF RAYNAUD’S PHENOMENON ARE NO OBSTACLE FOR BEING PHYSICALLY ACTIVE IN HEALTHY WOMEN

Background Women with primary Raynaud’s phenomenon (RP) often experience a decreased health related quality of life (HRQoL). A physically active lifestyle could have positive influence on vascular function and thus might improve HRQoL in women RP. Objectives To quantify the amount type physical activity (PA) sedentary behaviour, as well stress, (RP), to compare this behaviour without RP from large population-based cohort (Lifelines). Methods The connective tissue disease (CTD) screening questionnaire data Lifelines database that was available ≥ 18 years old used. This consists 30 questions detect possible CTD’s. total 19820 women, 929 18891 RP, all other comorbidities were included. By using questionnaires patient characteristics retrieved including stress. Results reported 300 min/week minutes moderate vigorous (MVPA), which more than (255 min/week). difference mainly due activities (p<.001). 74.3% complied enhancing PA guidelines (69.5% group p=.003). Time spent by 540 min/week, comparable time (540 p=.886). scored lower almost eight domains QoL (p<.05), except for functioning (p=.181). Regarding stress levels, List Threatening Experiences (LTE) showed no differences between groups (p=.226), however, Long-term Difficulties Inventory (LDI) higher level Furthermore, significantly younger (p<.001), had Body Mass Index (BMI) waist-hip ratio packyears (p<.001) healthier diet score compared Conclusion is first study structurally investigate population patients Most report they sufficient comply guidelines. seems showing obstacle being active. However, RP; research needed elucidate relation group, preferably objective measurement instruments assess PA. Acknowledgements biobank initiative has been made subsidies Dutch Ministry Health, Welfare Sport, Economic Affairs, University Medical Center Groningen, Northern Provinces Netherlands. There funding manuscript. Disclosure Interests None Declared.